Electron Transport Chain and Energy Production

In cellular biology, the electron transport chain is one of the steps in your cells processes that make energy from the foods you eat.   It is the third step of aerobic cellular respiration. Cellular respiration is the term for how your bodys cells make energy from food consumed. The electron transport chain is where most of the energy cells need to operate is generated. This chain is actually a series of protein complexes and electron carrier molecules within the inner membrane of cell mitochondria, also known as the cells powerhouse. Oxygen is required for  aerobic respiration  as the chain terminates with the donation of electrons to oxygen.   Key Takeaways: Electron Transport Chain The electron transport chain is a series of protein complexes and electron carrier molecules within the inner membrane of mitochondria that generate ATP for energy.Electrons are passed along the chain from protein complex to protein complex until they are donated to oxygen. During the passage of electrons, protons are pumped out of the mitochondrial matrix across the inner membrane and into the intermembrane space.The accumulation of protons in the intermembrane space creates an electrochemical gradient that causes protons to flow down the gradient and back into the matrix through ATP synthase. This movement of protons provides the energy for the production of ATP.The electron  transport chain is the third step of aerobic cellular respiration. Glycolysis and the Krebs cycle are the first two steps of cellular respiration. How Energy Is Made As electrons move along a chain, the movement or momentum is used to create  adenosine triphosphate (ATP). ATP is the main source of energy for many cellular processes including muscle contraction and cell division. Adenosine triphosphate (ATP) is a organic chemical that provides energy for cell. ttsz / iStock / Getty Images Plus Energy is released during cell metabolism when ATP is hydrolyzed. This happens when electrons are passed along the chain from protein complex to protein complex until they are donated to oxygen forming water.  ATP chemically decomposes to adenosine diphosphate (ADP) by reacting with water. ADP is in turn used to synthesize ATP. In more detail, as electrons are passed along a chain from protein complex to protein complex, energy is released and hydrogen ions (H) are pumped out of the mitochondrial matrix (compartment within the inner  membrane) and into the intermembrane space (compartment between the inner and outer membranes). All this activity creates both a chemical gradient (difference in solution concentration) and an electrical gradient (difference in charge) across the inner membrane. As more H  ions are pumped into the intermembrane space, the higher concentration of  hydrogen atoms  will build up and flow back to the matrix simultaneously powering the production of ATP by the protein complex ATP synthase. ATP synthase uses the energy generated from the movement of H  ions into the matrix for the conversion of ADP to ATP. This process of oxidizing molecules to generate energy for the production of ATP is called oxidative phosphorylation. The First Steps of Cellular Respiration Cellular respiration is a set of metabolic reactions and processes that take place in the cells of organisms to convert biochemical energy from nutrients into adenosine triphosphate (ATP), and then release waste products. normaals / iStock / Getty Images Plus The first step of cellular respiration is glycolysis. Glycolysis occurs in the cytoplasm and involves the splitting of one molecule of glucose into two molecules of the chemical compound pyruvate. In all, two molecules of ATP and two molecules of NADH (high energy, electron carrying molecule) are generated. The second step, called the citric acid cycle or Krebs cycle, is when pyruvate is transported across the outer and inner mitochondrial membranes into the mitochondrial matrix. Pyruvate is further oxidized in the Krebs cycle producing two more molecules of ATP, as well as NADH and FADH 2 molecules. Electrons from NADH and FADH2 are transferred to the third step of cellular respiration, the electron transport chain. Protein Complexes in the Chain There are four protein complexes  that are part of the electron transport chain that functions to pass electrons down the chain. A fifth protein complex serves to transport hydrogen ions back into the matrix. These complexes are embedded within the inner mitochondrial membrane.   Illustration of electron transport chain with oxidative phosphorylation. extender01 / iStock / Getty Images Plus Complex I NADH transfers two electrons to Complex I resulting in four H ions being pumped across the inner membrane. NADH is oxidized to NAD, which is recycled back into the Krebs cycle. Electrons are transferred from Complex I to a carrier molecule ubiquinone (Q), which is reduced to ubiquinol (QH2). Ubiquinol carries the electrons to Complex III. Complex II FADH2 transfers electrons to Complex II and the electrons are passed along to ubiquinone (Q). Q is reduced to ubiquinol (QH2), which carries the electrons to Complex III. No H ions are transported to the intermembrane space in this process. Complex III The passage of electrons to Complex III drives the transport of four more H ions across the inner membrane. QH2 is oxidized and electrons are passed to another electron carrier protein cytochrome C. Complex IV Cytochrome C passes electrons to the final protein complex in the chain, Complex IV. Two H ions are pumped across the inner membrane. The electrons are then passed from Complex IV to an oxygen (O2) molecule, causing the molecule to split. The resulting oxygen atoms quickly grab H ions to form two molecules of water. ATP Synthase ATP synthase moves H ions that were pumped out of the matrix by the electron transport chain back into the matrix. The energy from the influx of protons into the matrix is used to generate ATP by the phosphorylation (addition of a phosphate) of ADP. The movement of ions across the selectively permeable mitochondrial membrane and down their electrochemical gradient is called chemiosmosis. NADH generates more ATP than FADH2. For every NADH molecule that is oxidized, 10 H ions are pumped into the intermembrane space. This yields about three ATP molecules. Because FADH2 enters the chain at a later stage (Complex II), only six H ions are transferred to the intermembrane space. This accounts for about two ATP molecules. A total of 32 ATP molecules are generated in electron transport and oxidative phosphorylation. Sources Electron Transport in the Energy Cycle of the Cell. HyperPhysics, hyperphysics.phy-astr.gsu.edu/hbase/Biology/etrans.html.Lodish, Harvey, et al. Electron Transport and Oxidative Phosphorylation. Molecular Cell Biology. 4th Edition., U.S. National Library of Medicine, 2000, www.ncbi.nlm.nih.gov/books/NBK21528/.

Decision-Making Innovation - 782 Words

The term, ‘innovation’ refers to an act of doing something new (Dictionary) while the term, ‘decision making’ can be referred to as a ‘deliberation about the decision situation in order to make a choice’ (O’Sullivan, T. 1988). This paper intends to explore the relatedness between ‘Decision Making in Social Work’ and the research on innovation, â€Å"Investigating Innovation Using a Context: Community Based Child Care Services†. Social work aims to promote ‘social change, problem solving in human relationships and empowerment and liberation of people to enhance well-being’ (Gamble, D. N. Weil, M. 2010), which are associated with a series of decision making. Crises intervention is also an area, social workers persistently focus upon, and decision making, in this context, mostly appears to be very perplexing. Focusing on this challenge, Terence O’Sullivan (1988) argues that the ‘social workers need to be critically aware of the contexts, in which decisions are made’ (O’Sullivan, T. 1988, p. 41). O’Sullivan, however, refers to the context as ‘the requirement, structures and conditions surrounding the decision making’ ((O’Sullivan, T. 1988, p. 23). Critical awareness of the context, as referred by O’Sullivan (1988), requires skills and activities beyond the gathering of knowledge associated with the context. Critical awareness is an outcome of higher order cognitive process that requires critical thinking skills (Ennis, 1993), and reflective thinking skills (Dewey, 1933; Baron,Show MoreRelatedDisruptive Innovation : An Organization s Decision Making Process2564 Words   |  11 Pages Disruptive Innovation Dina M. Stewart University of Minnesota â€Æ' Disruptive Innovation Health care, like so many industries, has been rapidly changing over the past several decades. 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Critique Essay Example For Students

Critique Essay ?Melender, H. S. Lauri, S. (1999). Fears associated with pregnancy and childbirth-Experiences of women who have recently given birth Midwifery, 15(3), 178-183. This descriptive study was undertaken to describe fears associated with pregnancy and childbirth. Also to see whether women who have recently given birth feel that their fears were justified. A convenience sample of 20 women, 10 primipare and 10 multiparae were interviewed in the maternity units of two university hospitals in Finland. A qualitative study was used, and data were collected by semi-structured interviews held 2 or 3 days after childbirth. Datainterpretation was based on the method of content analysis. The authors found that the most common fears associated with pregnancy and childbirth wereconcerns with the babys well-being, the course of pregnancy, and childbirth. The fears found expression in different kinds of behaviors, emotions and physical sensations. Many of the participants felt that their fears had not been justified, but some maintained that their fears had been justifiable. The authors conclude that there was much inter-individual variation in the fears associated with pregnancy and childbirth. The findings further verify the importance that diagnosis during pregnancy is undertaken sensitively and that the care-giver remember that pregnant women may have very serious fears associated with pregnancy and childbirth. Critique:This study is timely, and in general, well done. The sample size was small, therefore, generalizations to an entire population cannot be made. The authors have done an adequate job of explaining their findings in understandable terms and document their rationale with a concise literature review. They give an appropriate rational for the convenience sampling of the Finnish women. The discussion is clearly written. The conclusions the authors draw are consistent withthe data presented, and they conclude with a well defined point that it may not be essential to try to protect women against these fears, but to give every pregnant women the opportunity to deal with her own fears and to obtain the help she needs in her situation. BibliographyMelender, H. S. Lauri, S. (1999). Fears associated with pregnancy and childbirth-Experiences of women who have recently given birth Midwifery, 15(3), 178-183.

Safest American Essays - Sedans, Coupes, Mid-size Cars, Muscle Cars

Safest American The Safest American made sedan by far is the 1994 Oldsmobile Cutlass Supreme LS. It is so because of the driving smoothness it offers on bumpy terrain, its size is bigger than a sports car, which enables it to sustain more damage. This car is also the safest because it is easy to reach the controls, so while you are driving you will not have to worry about leaning over to reach a button. The main good thing about this automobile is the price of it. You can now buy such a safe car for only sixteen thousand nine hundred ninety-five dollars. The price of this vehicle is more than descent when you look at all the features that it has. It has a drivers side airbag for extra protection. It also provides you with a three point on liter v-six engine and for-wheel anti-lock brakes, or ABS as some like to call it. If you think about it, this is a pretty impressive package. This price puts this car in range with some other notably safe cars such as the Ford Taurus and the Dodge Intrepid. It really does not matter though, since the LS is much safer. Weather can really get on your nerves, and that is why this vehicle has been added with rear-window and side-window defoggers to clear up any moisty mists that want to hang out on your glass. The car also has great traction, which was tested by the average human being, and not just Oldsmobile staff. These people say that the traction is nice and smooth, making this car perfect for rainy weather. Psychology Essays

13 Expository Essay Topics on Drug Use and Its Consequences

13 Expository Essay Topics on Drug Use and Its Consequences If you are writing an essay on drug use and its consequences, you might be in need of facts. Below are some facts that can help you support your claims: Both psychology and sociology seek to explain drug abuse, and each has their distinct perspective on the subject. The phrase ‘drug abuse’ implies excessive use of a controlled substance, resulting in negative consequences. While sociology emphasizes the possible influence of environmental, cultural and social aspects on drug abuse, psychology seeks to establish factors that exist in a person’s sub-conscious mind as influencing drug abuse. In fact, psychological and sociological factors may account for the prevalence of drug abuse. Defining drug abuse must acknowledge social context. Negative behaviour is connoted by the term ‘drug abuse,’ according to an article from DrugLibrary.org. However, sociology views behaviour as being positive or negative based on the social context of such behaviour. The same behaviour could take on a negative or positive hue, depending on the social circumstances. There are various sociological factors – such as the socio-economic status of a person that could influence drug abuse. For instance, having to cope with adverse environmental or social conditions could drive a person to abuse drugs. A drug abuser might be encouraged by mass media or his/ her peer group, either of which might in some manner validate his behaviour. The psychological perspective explaining the causes of drug abuse focuses on a drug abuser’s inner motivations rather than his/ her social circumstances. Psychology does not allow for the possibility that a drug abuser might deliberately opt to abuse drugs, even to the extent that his/ her behaviour could result in ruining their personal relationships or financial stability. The drug abuser’s behaviour could also lead to their imprisonment, hardly a desirable option. Instead the psychological perspective stresses that the drug abuser behaves as they do because of a biological predisposition to an addiction that is beyond their control. According to the website of the California State University at Northridge, drug abuse is attributable to several environmental and cultural factors that, however, fail to account for all instances of drug abuse. Psychology discounts sociology’s ability to provide an adequate explanation as to why even under similar environmental, social, and cultural circumstances, some people abuse drugs while others don’t. Social interaction among humans is also affected by drug abuse and can have a radical effect on your child’s relations with friends, family members and others. The entire family of a drug-abusing youth is affected psychologically, financially and emotionally. Teenage drug users tend to distant themselves from members of their family as well as from activities involving such family members. Additionally, they set a poor example for younger siblings. Drug use impairs their decision-making ability and judgment, thereby inducing hostility towards their family members and even causing them to steal money from their family members to buy drugs. There is an observed decline in the academic performance of teen drug abusers, who also reveal a greater propensity to absenting themselves from school and related activities. A higher drop-out rate has also been found among drug abusers, according to relevant research. Cognitive and behavioural problems may also interfere with the academic performance of youth who use alcohol and drugs. The academic performance of youth engaging in drug and alcohol abuse is also impacted by behavioural and cognitive problems concomitant with such substance abuse. Teenage drug abusers tend to alienate themselves from peers, and the related stigma is accompanied by the youth’s disengagement from community events and school. Teens who eschew drug use are best advised to keep a healthy distance from those who use drugs. As endorsed by experts, such youth are more likely to become drug users themselves if they associate with drug abusing peers and are exposed to the latter’s delinquent behaviour. There is a perceived correlation between substance abuse and delinquency. Quite often, drug-abusing youth face consequences such as arrest and adjudication, in which case the juvenile justice system intervenes. While a clear causal relationship between substance abuse and delinquency cannot be established or for that matter, even a causal relationship between delinquency and alcohol and drug use there is no denying the fact that the two behaviours are linked. Such linkage between substance abuse and delinquency often leads to youths associating with negative peer groups, in addition to problems in the youth’s domestic and academic environments. Drugs can have a negative and harmful effect on a person’s perception, concentration and motor functions, making drugged driving a major cause for concern. Driving under the influence of drugs can cause potential harm to the driver as well as others, owing to the increased possibility of accidents. For instance, a driver’s mental faculties, under the influence of Marijuana, can stay impaired for as long as three hours after ingesting the drug, which can stay in the driver’s system for as long as 24 hours. Roughly 15% of teen drug users (or one in six such individuals) have confessed to driving under the influence. Behaviour patterns of teens influenced by drug abuse also make them vulnerable to sexually transmitted diseases such as HIV/AIDS. This may be due to injecting drugs and sharing used needles. Alternatively, it could result from lack of judgment or controlled impulse while under the influence of drugs with mood-altering properties. This in turn would increase the possibility of engaging in sexual behaviour involving greater exposure to risk. Psychosocial dysfunctions such as withdrawal, apathy, developmental lags, and depression are among the mental health problems most commonly associated with adolescent substance abuse. Youth who abuse substances are more likely than youth who desist from drug use to fall prey to mental problems. These include suicidal thoughts that can lead to suicide or attempted suicide, apart from other mental health problems such as personality disorders, conduct problems, and depression. For instance, interference with psychomotor skills, learning, and short-term memory are mental health problems commonly associated with Marijuana use. The possibility drug addiction is never considered by somebody who uses them for the first time. However, almost invariably addiction is a consequence of using drugs that have a habit-forming quality. Addiction leads in turn to loss of judgement and control; stopping use of the drug can cause severe physical and psychological symptoms. These could manifest as stress, unhappiness, irritability and anxiety, among other symptoms. Some drugs could also induce withdrawal symptoms such as bone pain, diarrhoea, flu, tremors and, in rare instances, seizures. The brain function of long-term users of drugs can change pervasively. For instance, long-term use of Ecstasy can result in sleep disorders, anxiety, depression, and memory deficits. It is quite a serious issue to write on. That’s why it’s necessary to use only truthful information. Apply these facts along with the suggested topics on drug use and its consequences to outline a high quality text. But to complete the writing you should make use of our guide on expository essays. Good luck! References: Anderson, M., Coleman, S., Ford, W., Gorsuch, R., Kaplan, H., Kleber, H., Woody, G. (1989). From Theory to Practice: The Planned Treatment of Drug Users.  Substance Use Misuse,  24(2), 123-166. doi: 10.3109/10826088909047280 Barlow, J. (2010).  Substance misuse: The implications of research, policy and practice. London: Jessica Kingsley. DeSimone, J. (2002). Illegal Drug Use and Employment.  Journal of Labor Economics,  20(4), 952-977. doi: 10.1086/342893 Everett, T., Donaghy, M., Feaver, S. (2003).  Interventions for mental health: An evidence-based approach for physiotherapists and occupational therapists. New York: Butterworth-Heinemann. Ghodse, H., Guse, S. B., Helmchen, H. (1999).  Substance misuse. London: Lippincott Williams Wilkins. Millhorn, M., Monaghan, M., Montero, D., Reyes, M., Roman, T., Tollasken, R., Walls, B. (2009). North Americans Attitudes Toward Illegal Drugs.  Journal of Human Behavior in the Social Environment,  19(2), 125-141. doi: 10.1080/10911350802687075 Na;. (1988). Substance misuse.  Current Opinion in Psychiatry,  1(3), 381404. doi: 10.1097/00001504-198805000-00019 Pilgrim, D. (2005).  Key concepts in mental health. London: SAGE. Primack, B., Kraemer, K., Fine, M., Dalton, M. (2009). Media Exposure and Marijuana and Alcohol Use Among Adolescents.  Substance Use Misuse,  44(5), 722-739. doi: 10.1080/10826080802490097

About the U.S. House of Representatives

About the U.S. House of Representatives The United States is a large, fractured, diverse and yet still unified nation, and few government bodies reflect the paradox that is this country better than the House of Representatives. Key Takeaways: U.S. House of Representatives The House of Representatives is the lower chamber of the two legislative bodies in the United States federal government.The House is currently made up of 435 representatives- referred to as congressmen or congresswomen- who serve an unlimited number of two-year terms. The number of representatives from each state is based on the state’s population.As required by the Constitution, representatives must reside in the state from which they are elected, must have been a U.S. citizen for at least seven years, and be at least 25 years old.A representative’s primary duties include introducing, debating, and voting on bills, proposing amendments to bills, and serving on committees.The House has the exclusive powers to initiate all tax and spending bills and to impeach federal officials.   Metrics of the House The House is the lower of the two legislative bodies in the U.S. government. It has 435 members, with the number of representatives per state dependent upon that states population. House members serve two-year terms. Rather than represent their entire state, as Senate members do, they represent a specific district. This tends to give House members a closer link to their constituents-and more accountability, since they have but two years to satisfy voters before having to run for re-election. Also referred to as a congressman or congresswoman, a representative’s primary duties include introducing bills and resolutions, offering amendments and serving on committees.   Alaska, North Dakota, South Dakota, Montana and Wyoming, all sprawling but sparsely populated states, have just one representative each in the House; tiny states like Delaware and Vermont also send just one representative to the House. By contrast, California sends 53 representatives; Texas sends 32; New York sends 29, and Florida sends 25 representatives to Capitol Hill. The number of representatives each state is allotted is determined every 10 years in accordance with the federal census. Although the number has changed periodically through the years, the House has remained at 435 members since 1913, with shifts in representation occurring among different states. The system of House representation based on district population was part of the Great Compromise of the Constitutional Convention in 1787, which led to the Permanent Seat of Government Act establishing the nations federal capital in Washington, DC. The House assembled for the first time in New York in 1789, moved to Philadelphia in 1790 and then to Washington, DC, in 1800. The Powers of the House While the Senates more exclusive membership may make it seem the more powerful of the two chambers of Congress, the House is charged with a vital task: the power to raise revenue through taxes. The House of Representatives also has the power of impeachment, in which a sitting president, vice president or other civil officials such as judges may be removed for high crimes and misdemeanors, as enumerated in the Constitution. The House is solely responsible for calling for impeachment. Once it decides to do so, the Senate tries that official to determine whether he or she should be convicted, which means automatic removal from office. Leading the House House leadership rests with the speaker of the house, usually a senior member of the majority party. The speaker applies House rules and refers bills to specific House committees for review. The speaker is also third in line to the presidency, after the vice president. Other leadership positions include the majority and minority leaders who monitor legislative activity on the floor, and the majority and minority whips who ensure that House members vote according to their respective parties positions. The  House Committee System The House is divided into committees in order to tackle the complex and various matters on which it legislates. House committees study bills and hold public hearings, gathering expert testimony and listening to voters. If a committee approves a bill, it then puts it before the entire House for debate. House committees have changed and evolved over time. Current committees include those on: agriculture;appropriations;armed services;the budget, education, and labor;energy and commerce;financial services;foreign affairs;homeland security;House administration;judiciary;natural resources;oversight and government reform;rules;science and technology;small business;standards of official conduct;transportation and infrastructure;veterans affairs; andways and means. In addition, House members may serve on joint committees with Senate members. The Raucous Chamber Given the shorter terms of House members, their relative proximity to their constituents and their larger numbers, the House is generally the more fractious and partisan of the two chambers. Its proceedings and deliberations, like those of the Senate, are recorded in the Congressional Record, ensuring transparency in the legislative process. Phaedra Trethan is a freelance writer who also works as a copy editor for the Camden Courier-Post. She formerly worked for the Philadelphia Inquirer, where she wrote about books, religion, sports, music, films, and restaurants. Updated by Robert Longley

Criminal Justice Act Essay Example | Topics and Well Written Essays - 1500 words

Criminal Justice Act - Essay Example The 2003 criminal justice act allows the admittance of evidence against a person for a bad character during the criminal process. The new law was enforced in 2004 succeeding the previous common law and many of the statutory regulations that governed the bad character admissibility which was abolished following these changes. The new scheme that replaced them sets out conditions in which such evidence can be put into use in criminal procedures (Denis 2002) The new statute seems to have sent back the position in DPP v P. it would seem that the law disregards the attempt to keep away from inclination evidence following DPP. These changes have been manifested so much in the period after 1999 in cases like R v Humphris (2005), R v Nguyen (2005) and R v Black. Nonetheless, it’s evident that that criminal cat of 2003 discards some of the cases like an instance of the case of New South Wales Makin V Attorney-General-(Roberts & Zuckerman 2004). According to Lord Herschell, the crown was unable to adduce evidence and was inclined to indicate that the accused was guilty of other criminal acts part from those implicated by the indictment for the reasons of drawing conclusions that he is a person likely from the previous criminal record to have committed the felony for which he was to be tried. This outlawed line of thinking prevented the crown from putting up arguments the defendant was guilty based on his general predisposition to commit comparable types of felonies (Denis 2002).